Infinium Global Screening Array-24 Kit

This next-generation genotyping array provides a scalable, cost-effective solution for population genetics, pharmacogenomics studies, and precision medicine research. Read More...
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Fixed Content

Infinium Global Screening Array-24 v3.0 Kit (48 Samples)

20030770

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Infinium Global Screening Array-24 v3.0 Kit (288 Samples)

20030771

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Infinium Global Screening Array-24 v3.0 Kit (1152 Samples)

20030772

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Add-On Content

Infinium Global Screening Array-24+ v3.0 Kit (48 Samples)

20030773

Infinium Global Screening Array-24+ v3.0 Kit (288 Samples)

20030774

Infinium Global Screening Array-24+ v3.0 Kit (1152 Samples)

20030775


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Infinium Training

20015273

Product Highlights

Global Content

The Infinium Global Screening Array-24 BeadChip combines multi-ethnic genome-wide content, curated clinical research variants, and quality control (QC) markers for precision medicine research.

The genome-wide content was selected for high imputation accuracy at minor allele frequencies of >1% across all 26 1000 Genomes Project populations. The clinical research content includes variants with established disease associations, relevant pharmacogenomics markers, and curated exonic content based on ClinVar, NHGRI, PharmGKB, and ExAC databases. QC content enables sample identification and tracking for large-scale genomics and screening applications.

Widespread Adoption

With over 15 million samples worth of BeadChips sold, the Global Screening Array's global adoption provides a network of human disease researchers, healthcare networks, consumer genomics companies, and genomic service providers to help power discovery.

Robust Assay and High-Throughput Workflow

The array supports genotyping and CNV calling for sample types including saliva, blood, and buccal swabs. The format allows processing of hundreds to thousands of samples per week with a 3-day workflow for population-scale studies.

Broad Clinical Research Applications

The array provides a genomic tool for clinical research applications including disease risk profiling studies, pharmacogenomics research, wellness characterization, and complex disease discovery.

Version 3 of the Global Screening Array leverages the most up to date and relevant clinical research screening markers derived from ClinVar, CPIC, and PharmGKB.

As leading databases such as ClinVar continue to rapidly add new variants, Illumina is dedicated to ensuring the variants interrogated on the GSA remain updated and relevant. The launch of the Infinium GSA-24 v3.0 BeadChip includes an update of key variants found in ACMG 59 genes. A growing number of precision medicine research initiatives around the world are leveraging these variants to screen populations for the following applications:

  • Studying disease risk by investigating the role of ClinVar designated "Pathogenic" and "Likely Pathogenic" variants in the likelihood of developing a phenotype and the frequency of such alleles within a given population.
  • Stratifying samples to allow for cost savings by enabling a program to focus more elaborate testing on select samples that are flagged as having interesting or suspicious findings.
  • Incentivizing participation and providing value to participants through return of results, boosting project sample sizes and discovery power.

View Manifest (Array Content) Files

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Specifications

Product Comparison

Infinium Global Screening Array-24 Kit Infinium Multi-Ethnic Global-8 Kit Infinium Omni2.5-8 Kit
Description An economical next-generation genotyping array that enables population-scale genetics, translational research, variant screening studies, and precision medicine research by combining highly optimized multiethnic genome-wide content, curated clinical research variants, and QC markers.
Number of Markers Fixed markers: ~ 654,027
Custom marker add-on capacity: Up to 50,000
Fixed markers: ~2,381,000
Number of Samples 24 samples per array
Sample Throughput ~5760 samples/week max per iScan (throughput and scan times may vary based on laboratory and system configurations.)

Method-Specific Workflow Example

 

Case Studies and Feature Articles

Scalable High-Throughput Array Enables Ethnic Chinese Genome Database Development
Scalable High-Throughput Array Enables Ethnic Chinese Genome Database Development

Fast Infinium array analysis and broad genome coverage support personal genetic testing services and database development.

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Bringing Meaning to Genetic Information
Bringing Meaning to Genetic Information

MyDNA recently began partnering with Illumina customers using the Global Screening Array and Asian Screening Array in their genetic test offerings.

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Polygenic Risk Scores Could Become Useful Tools in the Physician's Toolbox
Polygenic Risk Scores Could Become Useful Tools in the Physician's Toolbox

Researchers perform large GWAS studies with the Global Screening Array to identify disease-associated DNA risk loci and develop PRSs for clinical validation.

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Genetic Testing Services Gain a Presence in India

The Global Screening Array and iScan System are helping Mapmygenome bring consumer genomics to a rapidly growing Indian population.

Read Article
Genetic Testing Services Gain a Presence in India

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