RNA sequencing (RNA-Seq) is revolutionizing the study of the transcriptome. A highly sensitive and accurate tool for measuring expression across the transcriptome, it is providing researchers with visibility into previously undetected changes occurring in disease states, in response to therapeutics, under different environmental conditions, and across a broad range of other study designs.
RNA-Seq allows researchers to detect both known and novel features in a single assay, enabling the detection of transcript isoforms, gene fusions, single nucleotide variants, and other features without the limitation of prior knowledge.
RNA-Seq with next-generation sequencing (NGS) is increasingly the method of choice for researchers studying the transcriptome. It offers numerous advantages over gene expression arrays.
Find out how Illumina NGS technology works and what types of experiments it enables.
Learn about 7 key RNA-Seq methods. Find out how they differ to help you determine the method most appropriate for your research.
A simple, scalable, cost-effective, rapid single-day solution for analyzing the coding transcriptome leveraging as little as 25 ng input of standard (non-degraded) RNA.
This cost-efficient, user-friendly, mid-throughput benchtop sequencer offers extreme flexibility to support new and emerging applications.
RNA-Seq and HLA typing are increasing the power and efficiency of a target discovery platform.Read Customer Interview
Transcriptomics and whole-genome shotgun sequencing provide researchers and pharmaceutical companies with data to refine drug discovery and development.Read Interview
Learn about read length and depth requirements for RNA-Seq and find resources to help with experimental design.Read Technical Bulletin
The new enhancements deliver solutions for studying RNA that provide rapid turnaround time, broad study flexibility and sequencing scalability, while delivering exceptional data quality for infectious disease, oncology and genetic disease research.Read Article
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